Radiological Features of Giant Cell Tumours of Bone

Howard, Emma L.; Gregory, Jonathan; Winn, Naomi; Flanagan, Adrienne; Cool, Paul

doi:10.7759/cureus.8793

Radiological Features of Giant Cell Tumours of Bone

Howard, Emma L.; Gregory, Jonathan; Winn, Naomi; Flanagan, Adrienne; Cool, Paul

Authors

Emma L. Howard

Jonathan Gregory

Naomi Winn

Adrienne Flanagan

Professor Wim Cool p.cool@keele.ac.uk

Abstract

Introduction The aim of this study was to evaluate radiological measurements to establish the origin of giant cell tumours of bone. Methods A multi-centre retrospective review was conducted of patients with histologically confirmed giant cell tumours of bone. Images were analysed to estimate the centre of the tumour. Measured from the joint line, the ratio between the distance of the centre of the tumour and the physeal scar was calculated. Results Ninety-five patients were included in the study. Two observers found the tumour to be arising from the metaphyseal area in 94% - 97% of the cases. There was good agreement between the measurements of observers (interclass correlation coefficient 0.71). Conclusion Giant cell tumours of bone appear to be arising from the metaphyseal region.

Journal Article Type	Article
Acceptance Date	Jun 18, 2020
Publication Date	Jun 24, 2020
Journal	Cureus
Print ISSN	2168-8184
Publisher	Springer
Peer Reviewed	Peer Reviewed
Volume	12
Issue	6
Article Number	e8793
DOI	https://doi.org/10.7759/cureus.8793
Publisher URL	https://www.cureus.com/articles/33081-radiological-features-of-giant-cell-tumours-of-bone