Skip to main content

Research Repository

Advanced Search

Radiobiology data of melanoma cells after low-energy neutron irradiation and boron compound administration

Radiobiology data of melanoma cells after low-energy neutron irradiation and boron compound administration Thumbnail


Abstract

The cold neutron beam at the PF1b line at the Institut Laue-Langevin (ILL), without fast neutrons and a low contribution of gamma rays, is a very suitable facility to measure cell damage following low-energy neutron irradiation. The biological damage associated with the thermal and the boron doses can be obtained in order to evaluate the relative biological effectiveness (RBE) for Boron Neutron Capture Therapy. Three different experiments were carried out on the A375 melanoma cell line: the first one in a hospital LINAC, to obtain the reference radiation data, and the other two at the ILL, in which the damage to cells with and without boron compounds added was measured.

Acceptance Date Apr 21, 2020
Publication Date Sep 1, 2020
Publicly Available Date Mar 28, 2024
Journal Applied Radiation and Isotopes
Print ISSN 0969-8043
Publisher Elsevier
Pages 109205 - ?
DOI https://doi.org/10.1016/j.apradiso.2020.109205
Publisher URL https://doi.org/10.1016/j.apradiso.2020.109205

Files




Downloadable Citations