McLaughlin, JA, Beal, J, Misirli, G, Grünberg, R, Bartley, BA, Scott-Brown, J, Vaidyanathan, P, Fontanarrosa, P, Oberortner, E, Wipat, A, Gorochowski, TE and Myers, CJ (2020) The Synthetic Biology Open Language (SBOL) Version 3: Simplified Data Exchange for Bioengineering. Frontiers in Bioengineering and Biotechnology, 8. ISSN 2296-4185

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The Synthetic Biology Open Language (SBOL) is a community-developed data standard that allows knowledge about biological designs to be captured using a machine-tractable, ontology-backed representation that is built using Semantic Web technologies. While early versions of SBOL focused only on the description of DNA-based components and their sub-components, SBOL can now be used to represent knowledge across multiple scales and throughout the entire synthetic biology workflow, from the specification of a single molecule or DNA fragment through to multicellular systems containing multiple interacting genetic circuits. The third major iteration of the SBOL standard, SBOL3, is an effort to streamline and simplify the underlying data model with a focus on real-world applications, based on experience from the deployment of SBOL in a variety of scientific and industrial settings. Here, we introduce the SBOL3 specification both in comparison to previous versions of SBOL and through practical examples of its use.

Item Type: Article
Uncontrolled Keywords: SBOL; data exchange; data standards; knowledge representation; synthetic biology.
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Divisions: Faculty of Natural Sciences > School of Computing and Mathematics
Depositing User: Symplectic
Date Deposited: 05 Oct 2020 11:28
Last Modified: 16 Mar 2021 16:13

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