Zare, M, Davoodi, P and Ramakrishna, S (2021) Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications. Nanomaterials, 11 (4). 1 - 25. ISSN 2079-4991

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Shape memory polymers (SMPs) as a relatively new class of smart materials have gained increasing attention in academic research and industrial developments (e.g., biomedical engineering, aerospace, robotics, automotive industries, and smart textiles). SMPs can switch their shape, stiffness, size, and structure upon being exposed to external stimuli. Electrospinning technique can endow SMPs with micro-/nanocharacteristics for enhanced performance in biomedical applications. Dynamically changing micro-/nanofibrous structures have been widely investigated to emulate the dynamical features of the ECM and regulate cell behaviors. Structures such as core-shell fibers, developed by coaxial electrospinning, have also gained potential applications as drug carriers and artificial blood vessels. The clinical applications of micro-/nanostructured SMP fibers include tissue regeneration, regulating cell behavior, cell growth templates, and wound healing. This review presents the molecular architecture of SMPs, the recent developments in electrospinning techniques for the fabrication of SMP micro-/nanofibers, the biomedical applications of SMPs as well as future perspectives for providing dynamic biomaterials structures.

Item Type: Article
Additional Information: This is the final published version of the article (version of record). It first appeared online via MDPI AG at - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: shape memory polymers, electrospinning, molecular architecture, micro-/nanostructures, actuation methods, biomedical applications
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine and Health Sciences > School of Pharmacy and Bioengineering
Depositing User: Symplectic
Date Deposited: 22 Apr 2021 08:47
Last Modified: 09 Jun 2021 13:29

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