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Urate Lowering for Blood Pressure Control in Adults: Another Nail in the Coffin?

Roddy, Edward

Urate Lowering for Blood Pressure Control in Adults: Another Nail in the Coffin? Thumbnail


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Abstract

Numerous observational studies have reported an association between serum urate and elevated blood pressure in adult populations (1). These observations, together with experimental in vivo studies, have generated substantial interest in the role of hyperuricaemia as a mediator of elevated blood pressure, with various postulated mechanisms, including activation of renin-angiotensin system, oxidative stress, reduced endothelial nitric oxide availability, and renal vasoconstriction (2).

Journal Article Type Article
Acceptance Date Mar 25, 2021
Online Publication Date Jun 8, 2021
Publication Date 2021-08
Publicly Available Date Mar 28, 2024
Journal Arthritis & Rheumatology
Print ISSN 2326-5191
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 73
Issue 8
Pages 1408-1411
DOI https://doi.org/10.1002/art.41751
Keywords Immunology, Rheumatology, Immunology and Allergy
Publisher URL https://onlinelibrary.wiley.com/doi/10.1002/art.41751

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