Paul Horrocks p.d.horrocks@keele.ac.uk
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence
Horrocks
Authors
Abstract
Reversible modification of proteins through the attachment of ubiquitin or ubiquitin-like modifiers is an essential post-translational regulatory mechanism in eukaryotes. The conjugation of ubiquitin or ubiquitin-like proteins has been demonstrated to play roles in growth, adaptation and homeostasis in all eukaryotes, with perturbation of ubiquitin-mediated systems associated with the pathogenesis of many human diseases, including cancer and neurodegenerative disorders.
Acceptance Date | Apr 24, 2008 |
---|---|
Publication Date | Apr 24, 2008 |
Publicly Available Date | Mar 28, 2024 |
Journal | PLoS One |
Print ISSN | 1932-6203 |
Publisher | Public Library of Science |
Pages | e2386 - ? |
DOI | https://doi.org/10.1371/journal.pone.0002386 |
Keywords | Apicomplexa, Plasmodium, Protein domains, Toxoplasma gondii, Ligases, Ubiquitin ligases, Cell cycle and cell division, Conjugated proteins |
Files
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence..pdf
(1.5 Mb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
You might also like
Pluripharmacological potential of Mascarene endemic plant leaf extracts
(2023)
Journal Article
In vitro and in vivo antimalarial activity and chemical profiling of sugarcane leaves.
(2022)
Journal Article
Downloadable Citations
About Keele Repository
Administrator e-mail: research.openaccess@keele.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search