Keele Research Repository

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Okokon, JE, Mobley, R, Edem, UA, Bassey, AI, Fadayomi, I, Drijfhout, FP ORCID: https://orcid.org/0000-0002-3210-8038, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Li, W-W ORCID: https://orcid.org/0000-0002-3706-6068 (2022) In vitro and in vivo antimalarial activity and chemical profiling of sugarcane leaves. Scientific Reports, 12 (1). 10250 - ?.

Luo, J, Mobley, R, Woodfine, S, Drijfhout, F, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732, Ren, X-D and Li, W-W (2022) Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger. Applied Microbiology and Biotechnology, 106 (7). pp. 2433-2444.

Hameed, H, King, E ORCID: https://orcid.org/0000-0001-7452-4518, Doleckova, K, Bartholomew, B, Hollinshead, J, Mbye, H, Ullah, I, Walker, K, Van Veelen, M, Abou-Akkada, S, Nash, R, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Price, HP ORCID: https://orcid.org/0000-0003-1537-4390 (2021) Temperate zone plant natural products – a novel resource for activity against tropical parasitic diseases. Pharmaceuticals, 14 (3). pp. 1-17.

Uche, FI, Guo, X, Okokon, J, Ullah, I, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732, Boateng, J, Huang, C and Li, W-W ORCID: https://orcid.org/0000-0002-3706-6068 (2020) In vivo efficacy and metabolism of the antimalarial cycleanine and improved in vitro antiplasmodial activity of novel semisynthetic analogues. Antimicrobial Agents and Chemotherapy, 65 (2).

Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732, Ullah, I, Wetzel, D, Sharma, R, Biagini, G and Mete, A (2019) The relative rate of kill of the MMV Malaria Box compounds provide links to the mode of antimalarial action and highlight scaffolds of medicinal chemistry interest. Journal of Antimicrobial Chemotherapy, 75 (2). pp. 362-370.

Czechowski, T, Rinaldi, M, Famodimu, M, Van Veelen, M, Larson, T, Winzer, T, Rathbone, D, Harvey, D, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Graham, I (2019) Flavonoid versus artemisinin anti-malarial activity in Artemisia annua whole-leaf extracts. Frontiers in Plant Science, 10.

Aldulaimi, O, Drijfhout, F ORCID: https://orcid.org/0000-0002-3210-8038, Uche, FI, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Li, W-W (2019) Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis. BMC Complementary and Alternative Medicine, 19 (1). 183 -?.

Berry, SL, Hameed, H, Thomason, A, Maciej-Hulme, ML, Saif Abou-Akkada, S, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Price, HP ORCID: https://orcid.org/0000-0003-1537-4390 (2018) Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays. PLoS Neglected Tropical Diseases, 12 (7). e0006639 - ?.

Cao, P, Li, W, Morris, A, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732, Yuan, C and Yang, Y (2018) Investigation of the antibiofilm capacity of peptide-modified stainless steel. Royal Society Open Science, 5 (3).

Harris, LM, Monsell, KM, Noulin, F, Famodimu, MT, Smargiasso, N, Damblon, C, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Merrick, CJ (2018) G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets. Antimicrobial Agents and Chemotherapy, 62 (3).

Johnson-Ajinwo, O, Ullah, I, Mbye, H, Richardson, A ORCID: https://orcid.org/0000-0003-1825-3375, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Li, W (2018) The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents. Bioorganic and Medicinal Chemistry Letters, 28 (7).

Boyle, MJ, Skidmore, MA, Dickerman, B, Cooper, L, Devlin, A, Yates, E, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732, Freeman, C, Chai, W and Beeson, JG (2017) Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. Antimicrobial Agents and Chemotherapy, 6 (11).

Aldulami, O, Uche, F, Hameed, H, Mbye, H, Ullah, I, Drijfhout, F, Claridge, T, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Li, W (2017) A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms. Journal of Ethnopharmacology, 198. pp. 221-225.

Ullah, I, Sharma, R, Biagini, G and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2016) A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials. Journal of Antimicrobial Chemotherapy, 72 (3). pp. 717-726.

Russell, K, Emes, R and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2015) Triaging informative cis -regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development. Parasites & Vectors, 8 (1). 81 -?.

Coultas, JA, Bodasing, N, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Cadwgan, A (2015) Lemierre's Syndrome: recognising a typical presentation of a rare condition. Case Reports in Infectious Diseases, 2015. 797415 -?.

Russell, K, Cheng, CH, Bizzaro, JW, Ponts, N, Emes, RD, Le Roch, K, Marx, KA and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2014) Homopolymer tract organization in the human malarial parasite Plasmodium falciparum and related Apicomplexan parasites. BMC Genomics, 15. 848 -?.

Russell, K, Hasenkamp, S, Emes, R and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2013) Analysis of the spatial and temporal arrangement of transcripts over intergenic regions in the human malarial parasite Plasmodium falciparum. BMC Genomics, 14. 267 - ?.

Hasenkamp, S, Sidaway, A, Devine, O, Roye, R and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2013) Evaluation of bioluminescence-based assays of anti-malarial drug activity. Malaria Journal, 12. 58 - ?.

Hasenkamp, S, Russell, KT and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2012) Comparison of the absolute and relative efficiencies of electroporation-based transfection protocols for Plasmodium falciparum. Malaria Journal, 11. 210 - ?.

Hasenkamp, S, Wong, EH and Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 (2012) An improved single-step lysis protocol to measure luciferase bioluminescence in Plasmodium falciparum. Malaria Journal, 11. 42 -?.

Ponts, N, Yang, J, Chung, DW, Prudhomme, J, Girke, T, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Le Roch, KG (2008) Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence. PLoS One, 3 (6). e2386 - ?.

Berry, S, Hameed, H, Thomason, A, Maciej-Hulme, M, Abou Akkada, S, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Price, H ORCID: https://orcid.org/0000-0003-1537-4390 Transgenic Leishmania mexicana expressing NanoLuc-PEST: evaluation of a new drug discovery screening tool. PLoS Neglected Tropical Diseases. (Submitted)