Keele Research Repository

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Gajdos, L, Blakeley, MP, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Devos, JM and Imberty, A (2022) Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding. Nature Communications, 13 (1).

Raskar, T, Niebling, S, Devos, JM, Yorke, BA, Härtlein, M, Huse, N, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Seydel, T and Pearson, AR (2022) Structure and diffusive dynamics of aspartate α-decarboxylase (ADC) liganded with D-serine in aqueous solution. Physical Chemistry Chemical Physics, 24 (34). 20336 - 20347.

Drago, VN, Devos, JM, Blakeley, MP, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Kovalevsky, AY, Schall, CA and Mueser, TC (2022) Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction. NPJ Microgravity, 8 (1). 13 - ?.

Ahmadi, D, Thompson, KC, García Sakai, V, Schweins, R, Moulin, M, Haertlein, M, Strohmeier, GA, Pichler, H, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Barlow, DJ, Lawrence, MJ and Foglia, F (2022) Nanoscale Structure and Dynamics of Model Membrane Lipid Raft Systems, Studied by Neutron Scattering Methods. Frontiers in Physics, 10.

Kehlenbeck, D-M, Traore, DAK ORCID: https://orcid.org/0000-0003-1001-4716, Josts, I, Sander, S, Moulin, M, Haertlein, M, Prevost, S, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477 and Tidow, H (2021) Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination. The Federation of European Biochemical Societies (FEBS) Journal.

Ramos, J, Laux, V, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Mossou, E, Larsen, S and Langkilde, AE (2021) The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme. Acta Crystallographica. Section D, Structural Biology, 77 (Pt 12). 1579 - 1590.

Borah, K, Mendum, TA, Hawkins, ND, Ward, JL, Beale, MH, Larrouy-Maumus, G, Bhatt, A, Moulin, M, Haertlein, M, Strohmeier, G, Pichler, H, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Noack, S, Goulding, CW, McFadden, J and Beste, DJV (2021) Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis. Molecular Systems Biology, 17 (5). e10280 - ?.

Ramos, J, Laux, V, Haertlein, M, Boeri Erba, E, McAuley, KE, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Mossou, E, Larsen, S and Langkilde, AE (2021) Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme. IUCRJ, 8 (Pt 3). 372 - 386.

Waldie, S, Sebastiani, F, Moulin, M, Del Giudice, R, Paracini, N, Roosen-Runge, F, Gerelli, Y, Prevost, S, Voss, JC, Darwish, TA, Yepuri, N, Pichler, H, Maric, S, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Haertlein, M and Cárdenas, M (2021) ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes: Effect of Protein Isoform and Membrane Composition. Frontiers in Chemistry, 9 (630152). 1- 15.

Sebastiani, F, Yanez Arteta, M, Lerche, M, Porcar, L, Lang, C, Bragg, RA, Elmore, CS, Krishnamurthy, VR, Russell, RA, Darwish, T, Pichler, H, Waldie, S, Moulin, M, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Lindfors, L and Cárdenas, M (2021) Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles. ACS Nano, 15 (4). 6709 - 6722.

Eves, BJ, Doutch, JJ, Terry, AE, Yin, H, Moulin, M, Haertlein, M, Forsyth, VT, Flagmeier, P, Knowles, TPJ, Dias, DM, Lotze, G, Seddon, AM and Squires, AM (2021) Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering. RSC Chem Biol, 2 (4). 1232 - 1238.

Gajdos, L, Blakeley, MP, Kumar, A, Wimmerová, M, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Imberty, A and Devos, JM (2021) Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions. Structure, 29 (9). pp. 1003-1013.

Dunne, OM, Gao, X, Nan, R, Gor, J, Adamson, PJ, Gordon, DL, Moulin, M, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477 and Perkins, SJ (2021) A Dimerization Site at SCR-17/18 in Factor H Clarifies a New Mechanism for Complement Regulatory Control. Frontiers in Immunology, 11. 601895 - ?.

Thomas, LH, Altaner, CM, Forsyth, VT, Mossou, E, Kennedy, CJ, Martel, A and Jarvis, MC (2021) Nanostructural deformation of high-stiffness spruce wood under tension. Sci Rep, 11 (1). 453 - ?.

Waldie, S, Sebastiani, F, Browning, K, Maric, S, Lind, TK, Yepuri, N, Darwish, TA, Moulin, M, Strohmeier, G, Pichler, H, Skoda, MWA, Maestro, A, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Bengtsson, E, Malmsten, M and Cárdenas, M (2020) Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 1865 (10). 158769 - ?.

Pedrosa-Rivera, M, Praena, J, Porras, I, Sabariego, MP, Köster, U, Haertlein, M, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Ramírez, JC, Jover, C, Jimena, D, Osorio, JL, Álvarez, P, Ruiz-Ruiz, C and Ruiz-Magaña, MJ (2020) Thermal Neutron Relative Biological Effectiveness Factors for Boron Neutron Capture Therapy from In Vitro Irradiations. Cells, 9 (10). pp. 1-14.

Pedrosa-Rivera, M, Ruiz-Magaña, MJ, Álvarez, P, Porras, I, Praena, J, Sabariego, MP, Köster, U, Haertlein, M, Forsyth, VT, Soldner, T, Ramírez, JC, Jover, C, Jimena, D, Osorio, JL, Postuma, I and Ruiz-Ruiz, C (2020) Radiobiology data of melanoma cells after low-energy neutron irradiation and boron compound administration. Applied Radiation and Isotopes, 163. 109205 - ?.

Gajdos, L, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Blakeley, MP, Haertlein, M, Imberty, A, Samain, E and Devos, JM (2020) Production of perdeuterated fucose from glyco-engineered bacteria. Glycobiology, 31 (2). pp. 151-158.

Moulin, M, Mossou, E, Signor, L, Kieffer-Jaquinod, S, Kwaambwa, HM, Nermark, F, Gutfreund, P, Mitchell, EP, Haertlein, M, Forsyth, VT and Rennie, AR (2019) Towards a molecular understanding of the water purification properties of Moringa seed proteins. Journal of Colloid and Interface Science, 554. pp. 296-304.

Foglia, F, Hazael, R, Meersman, F, Wilding, MC, Sakai, VG, Rogers, S, Bove, LE, Koza, MM, Moulin, M, Haertlein, M, Forsyth, VT and McMillan, PF (2019) In Vivo Water Dynamics in Shewanella oneidensis Bacteria at High Pressure. Scientific Reports, 9 (1). 8716 -?.

Maric, S, Lind, TK, Raida, MR, Bengtsson, E, Fredrikson, GN, Rogers, S, Moulin, M, Haertlein, M, Forsyth, VT, Wenk, MR, Pomorski, TG, Arnebrant, T, Lund, R and Cárdenas, M (2019) Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes. Scientific Reports, 9 (1). 7591 - ?.

Grimaldo, M, Lopez, H, Beck, C, Roosen-Runge, F, Moulin, M, Devos, JM, Laux, V, Härtlein, M, Da Vela, S, Schweins, R, Mariani, A, Zhang, F, Barrat, J-L, Oettel, M, Forsyth, VT, Seydel, T and Schreiber, F (2019) Protein Short-Time Diffusion in a Naturally Crowded Environment. Journal of Physical Chemistry Letters, 10 (8). 1709 - 1715.

Waldie, S, Moulin, M, Porcar, L, Pichler, H, Strohmeier, GA, Skoda, M, Forsyth, VT, Haertlein, M, Maric, S and Cárdenas, M (2019) The Production of Matchout-Deuterated Cholesterol and the Study of Bilayer-Cholesterol Interactions. Scientific Reports, 9 (1). 5118 - ?.

Yee, AW, Aldeghi, M, Blakeley, MP, Ostermann, A, Mas, PJ, Moulin, M, de Sanctis, D, Bowler, MW, Mueller-Dieckmann, C, Mitchell, EP, Haertlein, M, de Groot, BL, Boeri Erba, E and Forsyth, VT (2019) A molecular mechanism for transthyretin amyloidogenesis. Nature Communications, 10 (1).

White, J, Laux, V, Fraser, N, HeB, D, Haertlein, M and Forsyth, VT (2018) Deuterium effects on human serum albumin in solution. Physica B: Condensed Matter, 551. pp. 208-211.

Forsyth, VT and Moody, P (2018) Neutron scattering for the study of biological systems - major opportunities within a rapidly changing landscape. Acta Crystallographica. Section D, Structural Biology, 74 (12). 1126 -1128.

Nitsche, J, Josts, I, Heidemann, J, Mertens, HD, Maric, S, Moulin, M, Haertlein, M, Busch, S, Forsyth, VT, Svergun, DI, Uetrecht, C and Tidow, H (2018) Structural basis for activation of plasma-membrane Ca(2+)-ATPase by calmodulin. Communications Biology, 1.

Nitsche, J, Josts, I, Heidemann, J, Mertens, HD, Maric, S, Moulin, M, Haertlein, M, Busch, S, Forsyth, VT ORCID: https://orcid.org/0000-0003-0380-3477, Svergun, DI, Uetrecht, C and Tidow, H (2018) Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin. Communications Biology, 1 (1). 206 - ?.

Josts, I, Nitsche, J, Maric, S, Mertens, HD, Moulin, M, Haertlein, M, Prevost, S, Svergun, DI, Busch, S, Forsyth, VT and Tidow, H (2018) Conformational States of ABC Transporter MsbA in a Lipid Environment Investigated by Small-Angle Scattering Using Stealth Carrier Nanodiscs. Structure, 26 (8). 1072 - 1079.e4.

Kokotidou, C, Jonnalagadda, SVR, Orr, AA, Seoane-Blanco, M, Apostolidou, CP, van Raaij, MJ, Kotzabasaki, M, Chatzoudis, A, Jakubowski, JM, Mossou, E, Forsyth, VT, Mitchell, EP, Bowler, MW, Llamas-Saiz, AL, Tamamis, P and Mitraki, A (2018) A novel amyloid designable scaffold and potential inhibitor inspired by GAIIG of amyloid beta and the HIV-1 V3 loop. FEBS Letters, 592 (11). 1777 - 1788.

Campbell, RA, Tummino, A, Varga, I, Milyaeva, OY, Krycki, MM, Lin, S-Y, Laux, V, Haertlein, M, Forsyth, VT and Noskov, BA (2018) Adsorption of Denaturated Lysozyme at the Air-Water Interface: Structure and Morphology. Langmuir, 34 (17). 5020 - 5029.

Mizuta, R, Devos, JM, Webster, J, Ling, WL, Narayanan, T, Round, A, Munnur, D, Mossou, E, Farahat, AA, Boykin, DW, Wilson, WD, Neidle, S, Schweins, R, Rannou, P, Haertlein, M, Forsyth, VT and Mitchell, EP (2018) Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide. Nanoscale, 10 (12). pp. 5550-5558.

Moulin, M, Strohmeier, GA, Hirz, M, Thompson, KC, Rennie, AR, Campbell, RA, Pichler, H, Maric, S, Forsyth, VT and Haertlein, M (2018) Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris. Chemistry and Physics of Lipids, 212. 80 -87.

Waldie, S, Lind, TK, Browning, K, Moulin, M, Haertlein, M, Forsyth, VT, Luchini, A, Strohmeier, GA, Pichler, H, Maric, S and Cárdenas, M (2017) Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine. Langmuir, 34 (1). 472 - 479.

Wojtas, DH, Ayyer, K, Liang, M, Mossou, E, Romoli, F, Seuring, C, Beyerlein, KR, Bean, RJ, Morgan, AJ, Oberthuer, D, Fleckenstein, H, Heymann, M, Gati, C, Yefanov, O, Barthelmess, M, Ornithopoulou, E, Galli, L, Xavier, PL, Ling, WL, Frank, M, Yoon, CH, White, TA, Bajt, S, Mitraki, A, Boutet, S, Aquila, A, Barty, A, Forsyth, VT, Chapman, HN and Millane, RP (2017) Analysis of XFEL serial diffraction data from individual crystalline fibrils. IUCRJ, 4. 795 -811.

Semeraro, EF, Devos, JM, Porcar, L, Forsyth, VT and Narayanan, T (2017) In vivo analysis of the Escherichia coli ultrastructure by small-angle scattering. IUCRJ, 4. 751 -757.

Prigipaki, A, Papanikolopoulou, K, Mossou, E, Mitchell, EP, Forsyth, VT, Selimis, A, Ranella, A and Mitraki, A (2017) Laser processing of protein films as a method for accomplishment of cell patterning at the microscale. Biofabrication, 9 (4). 045004 - ?.

Deidda, G, Jonnalagadda, SVR, Spies, JW, Ranella, A, Mossou, E, Forsyth, VT, Mitchell, EP, Bowler, MW, Tamamis, P and Mitraki, A (2017) Self-Assembled Amyloid Peptides with Arg-Gly-Asp (RGD) Motifs As Scaffolds for Tissue Engineering. ACS BIOMATERIALS SCIENCE & ENGINEERING, 3 (7). 1404 - 1416.

Yee, AW, Blakeley, MP, Moulin, M, Haertlein, M, Mitchell, E and Forsyth, VT (2017) Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy. Journal of Applied Crystallography, 50 (2). 660 -664.

Jordan, A, Jacques, M, Merrick, C, Devos, J, Forsyth, VT, Porcar, L and Martel, A (2016) SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering. Journal of Applied Crystallography, 49 (Pt 6). 2015 - 2020.

Dunne, O, Weidenhaupt, M, Callow, P, Martel, A, Moulin, M, Perkins, S, Haertlein, M and Forsyth, VT (2016) Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density culture. European Biophysics Journal, 46 (5). pp. 425-432.

Dunne, O, Weidenhaupt, M, Callow, P, Martel, A, Moulin, M, Perkins, SJ, Haertlein, M and Forsyth, VT (2016) Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density cultures. European Biophysics Journal, 46 (5). pp. 425-432.

Cuypers, MG, Mason, SA, Mossou, E, Haertlein, M, Forsyth, VT and Mitchell, EP (2016) Macromolecular structure phasing by neutron anomalous diffraction. Scientific Reports, 6. 31487 - ?.

Yee, AW, Moulin, M, Breteau, N, Haertlein, M, Mitchell, EP, Cooper, JB, Boeri Erba, E and Forsyth, VT (2016) Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses. Angew Chem Int Ed Engl, 128 (32). pp. 9438-9442.

van der Maarel, JRC, Guttula, D, Arluison, V, Egelhaaf, SU, Grillo, I and Forsyth, VT (2016) Structure of the H-NS-DNA nucleoprotein complex. Soft Matter, 12 (15). 3636 - 3642.

Forsyth, VT (2015) Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation. Biochimica et Biophysica Acta - Biomembranes, 1858 (4). pp. 640-652.

Thomas, LH, Forsyth, VT, Martel, A, Grillo, I, Altaner, CM and Jarvis, MC (2015) Diffraction evidence for the structure of cellulose microfibrils in bamboo, a model for grass and cereal celluloses. BMC Plant Biology, 15. 153 - ?.

Edlich-Muth, C, Artero, JB, Callow, P, Przewloka, MR, Watson, AA, Zhang, W, Glover, DM, Debski, J, Dadlez, M, Round, AR, Forsyth, VT and Laue, ED (2015) The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. J Mol Biol, 427 (10). 1949 - 1963.

Haupt, M, Blakeley, MP, Fisher, SJ, Mason, SA, Cooper, JB, Mitchell, EP and Forsyth, VT (2014) Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein. IUCrJ, 1 (Pt 6). 429 - 438.