Keele Research Repository

A

Ahmadipour, S, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Field, RA and Miller, GJ ORCID: https://orcid.org/0000-0001-6533-3306 (2022) Sweet targets: sugar nucleotide biosynthesis inhibitors. Future Medicinal Chemistry.

Akin, N, Richani, D, Liao, X, Zhao, Y, Herta, A-C, Billooye, K, Stocker, WA, Mottershead, D ORCID: https://orcid.org/0000-0003-2593-0725, Harrison, CA, Smitz, J, Anckaert, E and Gilchrist, RB (2022) Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM. Journal of Assisted Reproduction and Genetics.

Al-Riyahee, AAA, Horton, PN, Coles, SJ, Berry, C, Horrocks, PD ORCID: https://orcid.org/0000-0003-3981-0732, Pope, SJA and Amoroso, AJ (2022) N,N'-Substituted thioureas and their metal complexes: syntheses, structures and electronic properties. Dalton Transactions, 51 (9). pp. 3531-3545.

Alrosan, Khaled Jamal Jad Allah ORCID: https://orcid.org/0000-0001-5507-8938 (2022) Use of nanoparticles to improve the therapeutic index of navitoclax. Doctoral thesis, Keele University.

Aminian, A, Sgueglia, GA, Wiemer, M, Kefer, J, Gasparini, GL, Ruzsa, Z, van Leeuwen, MAH, Ungureanu, C, Leibundgut, G, Vandeloo, B, Kedev, S, Bernat, I, Ratib, K, Iglesias, JF, Al Hage, E, Posteraro, GA, Pascut, D, Maes, F, Regazzoli, D, Kakonyi, K, Meijers, TA, Colletti, G, Krivoshei, L, Lochy, S, Zafirovska, B, Horák, D, Nolan, J ORCID: https://orcid.org/0000-0001-6442-496X, Degrauwe, S, Tobita, K and Saito, S (2022) Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial. JACC: Cardiovascular Interventions, 15 (12). 1191 - 1201.

B

Bahrami, Z, Hatamian, N, Talkhabi, M, Zand, E, Mottershead, DG and Fathi, R (2022) Granulosa Cell Conditioned Medium Enhances The Rate of Mouse Oocyte In Vitro Maturation and Embryo Formation. Cell Journal (Yakhteh), 24 (10). 620 - 627.

Barreto, S, Al-Zubaidi, MA, Dale, TP, Worrall, AJ, Kapacee, Z, Kimber, SJ, Sulé-Suso, J, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 and Rutter, AV ORCID: https://orcid.org/0000-0003-2990-1163 (2022) Physiological Oxygen Causes the Release of Volatile Organic Compounds from Human Pluripotent Stem Cells with Possible Roles in Maintaining Self-Renewal and Pluripotency. Preprints.

Bernardo Harrington, Gabriel Mateus ORCID: https://orcid.org/0000-0001-6075-3619 (2022) A multimodal approach to biomarker discovery for spinal cord injury. Doctoral thesis, Keele University.

Bhunia, S, O'Brien, S, Ling, Y, Huang, Z, Wu, P ORCID: https://orcid.org/0000-0003-0011-5636 and Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 (2022) New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Scientific Reports, 12 (1). 5109 - ?.

Brown, SJ ORCID: https://orcid.org/0000-0001-9671-7054, Kline, RA, Synowsky, SA, Shirran, SL, Holt, I, Sillence, KA, Claus, P, Wirth, B, Wishart, TM and Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X (2022) The proteome signatures of fibroblasts from patients with severe, intermediate and mild spinal muscular atrophy show limited overlap. Cells, 11 (17).

C

Cabrera, D ORCID: https://orcid.org/0000-0001-7912-9939, Eizadi Sharifabad, M, Ranjbar, J, Telling, ND ORCID: https://orcid.org/0000-0002-2683-5546 and Harper, AGS ORCID: https://orcid.org/0000-0003-2413-4823 (2022) Clot-Targeted Magnetic Hyperthermia Permeabilizes Blood Clots to Make Them More Susceptible to Thrombolysis. Journal of Thrombosis and Haemostasis.

Channa, KK, Venables, R and White, S ORCID: https://orcid.org/0000-0003-0096-251X (2022) Elderly Patients' Perspectives on the Acceptability of Deprescribing Medicines: A Qualitative Study Protocol. International Journal of Qualitative Methods, 21.

Chen, R ORCID: https://orcid.org/0000-0001-8745-5902, Ahmed, MA and Forsyth, NR (2022) Dimethyloxalylglycine (DMOG), a Hypoxia Mimetic Agent, Does Not Replicate a Rat Pheochromocytoma (PC12) Cell Biological Response to Reduced Oxygen Culture. Biomolecules, 12 (4). 541 - 541.

Choi, PJ, Tomek, P, Tercel, M, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Park, TIH, Cooper, EA, Denny, WA, Jose, J and Leung, E (2022) Conjugation of Palbociclib with MHI-148 Has an Increased Cytotoxic Effect for Breast Cancer Cells and an Altered Mechanism of Action. Molecules, 27 (3). pp. 1-14.

Cork, T and White, S ORCID: https://orcid.org/0000-0003-0096-251X (2022) Exploring community pharmacists' use of health literacy interventions in their everyday practice. Research in Social and Administrative Pharmacy, 18 (11). pp. 3948-3952.

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Dale, TP ORCID: https://orcid.org/0000-0001-9461-8220, Santer, M, Haris, M, Zuo, W and Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 (2022) Hypoxic conditions promote a proliferative, poorly differentiated, and pro-secretory phenotype in COPD lung tissue progenitor cells in vitro. bioRxiv.

Dale, TP ORCID: https://orcid.org/0000-0001-9461-8220, Santer, M, Iftikar, S, Haris, M and Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 (2022) SUCCESSFUL ISOLATION AND CULTURE OF MULTIPOTENTIAL DISTAL AIRWAY STEM CELLS FROM COPD PATIENTS. TISSUE ENGINEERING PART A, 28 (S1). S451 - S452.

Dhillon, K, Aizel, K, Broomhall, TJ, Secret, E, Goodman, T, Rotherham, M, Telling, ND ORCID: https://orcid.org/0000-0002-2683-5546, Siaugue, JM, Ménager, C, Fresnais, J, Coppey, M, El Haj, AJ ORCID: https://orcid.org/0000-0003-3544-5678 and Gates, MA ORCID: https://orcid.org/0000-0002-2901-1083 (2022) Directional control of neurite outgrowth: emerging technologies for Parkinson's disease using magnetic nanoparticles and magnetic field gradients. Journal of the Royal Society Interface, 19 (196). 20220576 - ?.

Dogan, F, Al Jumaily, RK, Kitchen, M and Forsyth, N ORCID: https://orcid.org/0000-0001-5156-4824 (2022) Physoxia influences global and gene-specific methylation in pluripotent stem cells. bioRxiv.

Dogan, Fatma (2022) Determining the role of epigenetics in telomerase regulation. Doctoral thesis, Keele University.

Dragomanova, S, Lazarova, M, Munkuev, A, Suslov, E, Volcho, K, Salakhutdinov, N, Bibi, A, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Tzvetanova, E, Alexandrova, A, Georgieva, A, Uzunova, D, Stefanova, M, Kalfin, R and Tancheva, L (2022) New Myrtenal-Adamantane Conjugates Alleviate Alzheimer's-Type Dementia in Rat Model. Molecules, 27 (17).

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Echevarria, Iria (2022) Remote control healing for osteoarthritis repair. Doctoral thesis, Keele University.

Edwards-Smallbone, J, Jensen, A, Roberts, L, Totanes, FI, Hart, SR ORCID: https://orcid.org/0000-0003-0521-6284 and Merrick, CJ (2022) Plasmodium falciparum GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA. Frontiers in Cellular and Infection Microbiology, 12.

Emery, N, Strachan, K, Kulshrestha, R, Kuiper, JH ORCID: https://orcid.org/0000-0002-7023-4078 and Willis, T (2022) Evaluating the Feasibility and Reliability of Remotely Delivering and Scoring the North Star Ambulatory Assessment in Ambulant Patients with Duchenne Muscular Dystrophy. Children, 9 (5). 728 - 728.

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Fadayomi, I, Sari, S, Kitchen, MO ORCID: https://orcid.org/0000-0002-1124-2940, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 and Li, W-W ORCID: https://orcid.org/0000-0002-3706-6068 (2022) Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells. Pharmacological Research - Modern Chinese Medicine, 3 (100074).

Fletcher, M, van der Molen, T, Lenney, W, Boucot, I, Aggarwal, B and Pizzichini, E (2022) Primary Care Management of Asthma Exacerbations or Attacks: Impact of the COVID-19 Pandemic. Advances in Therapy.

Frisher, M (2022) What can Jane Goodall teach us about addiction? Drugs: Education, Prevention and Policy. 1 - 5.

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Garofalo, M, Jeon, Y-J, Nuovo, GJ, Middleton, J, Secchiero, P, Joshi, P, Alder, H, Nazaryan, N, Di Leva, G ORCID: https://orcid.org/0000-0001-6759-8682, Romano, G, Crawford, M, Nana-Sinkam, P and Croce, CM (2022) Correction: MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer. PLoS One, 17 (4). e0267628 - ?.

Ghanem, M, Brown, SJ ORCID: https://orcid.org/0000-0001-9671-7054, Mohamed, AEAT and Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X (2022) A Meta-summary and Bioinformatic Analysis Identified Interleukin 6 as a Master Regulator of COVID-19 Severity Biomarkers. Cytokine, 159 (156011).

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Hart, SR ORCID: https://orcid.org/0000-0003-0521-6284, Smallbone-Edwards, J, Merrick, C, Jensen, A, Roberts, L and Totanes, F (2022) Plasmodium falciparum GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA. Frontiers in Cellular and Infection Microbiology. (In Press)

Hoang, DM, Pham, PT, Bach, TQ, Ngo, ATL, Nguyen, QT, Phan, TTK, Nguyen, GH, Le, PTT, Hoang, VT, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824, Heke, M and Nguyen, LT (2022) Stem cell-based therapy for human diseases. Signal Transduction and Targeted Therapy, 7 (1). 272 - ?.

Hu, B, Rotherham, M ORCID: https://orcid.org/0000-0002-9297-7681, Farrow, N, Roach, P ORCID: https://orcid.org/0000-0003-4135-9733, Dobson, J and El Haj, AJ ORCID: https://orcid.org/0000-0003-3544-5678 (2022) Immobilization of Wnt Fragment Peptides on Magnetic Nanoparticles or Synthetic Surfaces Regulate Wnt Signaling Kinetics. International Journal of Molecular Sciences, 23 (17).

Hulme, CH ORCID: https://orcid.org/0000-0002-4961-2185, Garcia, J ORCID: https://orcid.org/0000-0002-7811-3078, Freeman, R, Kiely, N, Williams, D, Wright, J and Wright, KT ORCID: https://orcid.org/0000-0001-8842-5908 (2022) Juvenile Chondrocytes: Novel Alternatives for Allogeneic Cell Therapy? In: International Cartilage Regeneration and Joint Preservation Society (ICRS) World Congress 2022. (In Press)

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Ivankin, DI, Dyrkheeva, NS, Zakharenko, AL, Ilina, ES, Zarkov, TO, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Luzina, OA, Volcho, KP, Salakhutdinov, NF and Lavrik, OI (2022) Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and docking. Bioorganic & Medicinal Chemistry Letters, 73 (128909).

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Javanbakht, M, Mashayekhi, A, Carlson, A, Moloney, E, Snow, M, Murray, J and Spalding, T (2022) Cost-Effectiveness Analysis of a Medial Meniscus Replacement Prosthesis for the Treatment of Patients with Medial Compartment Pain in the United Kingdom. Pharmacoeconomics.

Jenkins, S, Zhu, L, Dallas, M and Chen, R ORCID: https://orcid.org/0000-0001-8745-5902 (2022) Editorial: Neuroinflammation in hypoxia and ischaemia. Frontiers in Molecular Biosciences, 9.

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Kyoseva, Ana Yuliyanova (2022) A novel scaffold for cell-based lung tissue engineering. Doctoral thesis, Keele University.

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Lamparelli, EP, Ciardulli, MC, Giudice, V, Scala, P, Vitolo, R, Dale, TP ORCID: https://orcid.org/0000-0001-9461-8220, Selleri, C, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824, Maffulli, N ORCID: https://orcid.org/0000-0002-5327-3702 and Della Porta, G (2022) 3D in-vitro cultures of human bone marrow and Wharton's jelly derived mesenchymal stromal cells show high chondrogenic potential. Frontiers in Bioengineering and Biotechnology, 10 (986310). -.

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Maidment, I, Wong, G, Duddy, C, Upthegrove, R, Oduola, S, Allen, K, Jacklin, S ORCID: https://orcid.org/0000-0001-7648-7247, Howe, J and MacPhee, M (2022) Medication optimisation in severe mental illness (MEDIATE): protocol for a realist review. BMJ Open, 12 (1). e058524 - ?.

Monaco, G, Qawasmi, F, El Haj, AJ ORCID: https://orcid.org/0000-0003-3544-5678, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 and Stoddart, MJ (2022) Chondrogenic differentiation of human bone marrow MSCs in osteochondral implants under kinematic mechanical load is dependent on the underlying osteo component. Frontiers in Bioengineering and Biotechnology, 10. 998774 - ?.

Mottershead, D ORCID: https://orcid.org/0000-0003-2593-0725 (2022) Granulosa Cell Conditioned Medium Enhances The Rate of Mouse Oocyte In Vitro Maturation and Embryo Formation. Cell Journal (Yakhteh), 24 (10). 620 - 627.

Munkuev, AA, Dyrkheeva, NS, Kornienko, TE, Ilina, ES, Ivankin, DI, Suslov, EV, Korchagina, DV, Gatilov, YV, Zakharenko, AL, Malakhova, AA, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Volcho, KP, Salakhutdinov, NF and Lavrik, OI (2022) Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan. Molecules, 27 (11).

Murphy, LJ, Fuller, H ORCID: https://orcid.org/0000-0001-8868-896X, Willan, PLT and Gates, M (2022) An Anatomy of the Blood Eagle: The Practicalities of Viking Torture. Speculum, 97 (1). pp. 1-39.

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O'Connor, S, Le Bihan, Y-V, Westwood, IM, Liu, M, Mak, OW, Zazeri, G, Povinelli, APR, Jones, AM, van Montfort, R, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512 and Collins, I (2022) Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70. Molecules, 27 (3).

Okokon, JE, Etuk, IC, Thomas, PS, Drijfhout, FP ORCID: https://orcid.org/0000-0002-3210-8038, Claridge, TDW and Li, W-W ORCID: https://orcid.org/0000-0002-3706-6068 (2022) In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum. Biomedicine & Pharmacotherapy, 151.

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Patabendige, A and Chen, R ORCID: https://orcid.org/0000-0001-8745-5902 (2022) Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke. Neural Regeneration Research, 17 (12). 2666 - 2668.

Pervan, M, Marijan, S, Markotić, A, Pilkington, LI, Haverkate, NA, Barker, D, Reynisson, J ORCID: https://orcid.org/0000-0003-4174-9512, Meić, L, Radan, M and Čikeš Čulić, V (2022) Novel Thieno [2,3-b]pyridine Anticancer Compound Lowers Cancer Stem Cell Fraction Inducing Shift of Lipid to Glucose Metabolism. International Journal of Molecular Sciences, 23 (19).

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Ranjbar, J, Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 and Harper, AGS ORCID: https://orcid.org/0000-0003-2413-4823 (2022) Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation. Platelets (London), 34 (1).

Reader, KL, John-McHaffie, S, Zellhuber-McMillan, S, Jowett, T, Mottershead, DG, Cunliffe, HE and Gold, EJ (2022) Activin B and Activin C Have Opposing Effects on Prostate Cancer Progression and Cell Growth. Cancers, 15 (1). 147 - 147.

Rotherham, M ORCID: https://orcid.org/0000-0002-9297-7681, Moradi, Y, Nahar, T, Mosses, D, Telling, ND ORCID: https://orcid.org/0000-0002-2683-5546 and El Haj, AJ ORCID: https://orcid.org/0000-0003-3544-5678 (2022) Magnetic activation of TREK1 triggers stress signalling and regulates neuronal branching in SH-SY5Y cells. Frontiers in Medical Technology, 4. 981421 - ?.

Rotherham, M, Nahar, T, Broomhall, TJ, Telling, ND ORCID: https://orcid.org/0000-0002-2683-5546 and El Haj, AJ ORCID: https://orcid.org/0000-0003-3544-5678 (2022) Remote magnetic actuation of cell signalling for tissue engineering. Current Opinion in Biomedical Engineering, 24 (100410).

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Sandhu, AK, Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 and Li, W-W ORCID: https://orcid.org/0000-0002-3706-6068 (2022) In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants─Systematic Review and Meta-Analysis. ACS Biomaterials Science and Engineering, 8 (5). pp. 1749-1762.

Scott, Natasha ORCID: https://orcid.org/0000-0002-7000-1995 (2022) Polypharmacy in atrial fibrillation: An analysis of prospective outcomes using the Clinical Practice Research Datalink (CPRD). Doctoral thesis, Keele University.

Shephard, MT, Merkhan, MM and Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 (2022) Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent. International Journal of Molecular Sciences, 23 (21).

Singh, Ayesha ORCID: https://orcid.org/0000-0002-4062-4921 (2022) Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke. Doctoral thesis, Keele University.

Storey, E and Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X (2022) Genotype-phenotype correlations in human diseases caused by mutations of LINC complex-associated genes: a systematic review and meta-summary. Cells, 11 (24).

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Thayer, N, White, S ORCID: https://orcid.org/0000-0003-0096-251X and Frisher, M (2022) Use of path analysis to predict changes to community pharmacy and GP emergency hormonal contraception (EHC) provision in England. BMJ Open, 12 (11). e059039 - e059039.

Thayer, Nicholas Mark ORCID: https://orcid.org/0000-0003-1127-9433 (2022) Factors influencing the commissioning and provision of community pharmacy Emergency Hormonal Contraception services in England. Doctoral thesis, Keele University.

Thayer, N, White, S ORCID: https://orcid.org/0000-0003-0096-251X and Frisher, M (2022) Describing the impact of community pharmacy organisation type on emergency hormonal contraception services in England. International Journal of Pharmacy Practice.

Thompson, J ORCID: https://orcid.org/0000-0001-9372-3846, Jacklin, S ORCID: https://orcid.org/0000-0001-7648-7247, Hutchinson, A, Norburn, L, Maddock, K, Maskrey, N and Underhill, J (2022) The creation of an online learning resource to support the implementation of the nice shared decision making guideline. Pharmacoepidemiology and Drug Safety, 31 (S1). 7 - 7.

Trivedi, R, John, J, Ghodke, A, Trivedi, J, Munigangaiah, S, Dheerendra, S, Balain, B, Ockendon, M and Kuiper, JH ORCID: https://orcid.org/0000-0002-7023-4078 (2022) Intrathecal morphine in combination with bupivacaine as pre-emptive analgesia in posterior lumbar fusion surgery: a retrospective cohort study. Journal of Orthopaedic Surgery and Research, 17 (1).

Tunnage, B, Woodhouse, LJ, Dixon, M, Anderson, C, Ankolekar, S, Appleton, J, Cala, L, England, T, Krishnan, K, Havard, D, Mair, G, Muir, K, Phillips, S, Potter, J, Price, C, Randall, M, Robinson, TG, Roffe, C ORCID: https://orcid.org/0000-0002-5259-6649, Sandset, E, Siriwardena, N, Scutt, P, Wardlaw, JM, Sprigg, N and Bath, PM (2022) Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial. BMC Emergency Medicine, 22 (1).

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Wang, J, Roberts, S ORCID: https://orcid.org/0000-0003-1835-327X, Li, W and Wright, K (2022) Phenotypic characterization of regional human meniscus progenitor cells. Frontiers in Bioengineering and Biotechnology, 10. 1003966 - ?.

Watkins, C, Tishkovskaya, S, Brown, C, Sutton, C, Garcia, YS, Forshaw, D, Prescott, G, Thomas, L, Roffe, C ORCID: https://orcid.org/0000-0002-5259-6649, Booth, J, Bennett, K, Roe, B, Hollingsworth, B, Mateus, C, Britt, D and Panton, C (2022) Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT. Health Technology Assessment, 26 (31). 1 - 88.

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Xie, B, Njoroge, W, Dowling, LM, Sulé-Suso, J, Cinque, G and Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 (2022) Detection of lipid efflux from foam cell models using a label-free infrared method. Analyst.